(NU2076) The Supply and Installation of a High-Plexed Platform for Gene Expression Analysis with Spatial Resolution at Single-Cell Scale

Description

The Faculty of Medical Sciences (FMS) within Newcastle University conducts significant discovery and clinical research on human tissue (healthy and diseased) as well as tissues from other relevant biological models. As part of an MRC equipment award, the University is seeking to purchase a technology that can measure multiple X on various tissues and cellular samples with single-cell spatial resolution. Due to the nature and complexity of the biological/clinical questions, the system must be able to detect a minimum of X protein biomarkers on the same tissue/cell sample. Such a platform will underpin existing work by the FMS Biomedical Research Facilities including, Flow Cytometry, Bioimaging, Genomics, Human Developmental Biology Resource (HDBR) and other single cell technologies. This tender process is for an analysis platform that is able to detect and quantitate over X with single-cell level spatial resolution in various tissue sections (fixed/frozen and formalin-fixed paraffin embedded – FFPE- samples) as well as immobilised suspension/adherent primary cells and cell lines. The contract cannot be divided into Lots because one integrated system is required. Keywords: Gene Expression Platform, High Plexed, Spatial Resolution, Single Cell