Automated Dissolution Platform for CMAC

Description

This Prior Information Notice (PIN) relates to a project to establish an agreement for the supply of an Automated Dissolution Platform for CMAC. Lot 1: CMAC is looking transform its dissolution testing capability with the addition of a fully automated system to our existing world class analytical facilities in the Technology and Innovation Centre at the University of Strathclyde. Dissolution testing is a key part of our overall analytical capability, supporting our extensive research programme and our partnerships with Tier 1 (industrial pharmaceutical) partners. The new equipment must be able to perform multiple 100 % unattended dissolution runs including media preparation, vacuum de-gassing, gravimetric vessel filling, multiple sample additions, sampling (resident probe and auto-lift), in vessel temperature monitoring, filtration, fast media change in line with USP requirements whilst running a test and self-cleaning. It must also be possible to obtain results in real-time with integrated spectroscopy (eg UV-Vis) and/or collect samples offline for different analytical techniques such as HPLC. In line with CMAC’s digital agenda, the software must be able to communicate with other physical testing equipment like fully automated hardness testers, balances, loss on drying equipment to generate a report of the test runs and store all data in standard formats. It must also be able to connect to an external database and have options for bidirectional OPC (Open Platform Communication) to interface with control software to read data and start runs. It is anticipated 3 years servicing of the equipment will also be covered.