Multiplex Spatial Biology Digital Imaging Platform using DNA bar-coding technology

Description

The University of Dundee School of Medicine require a spatial biology platform to embed this cutting-edge technology to map the spatial architecture of cells and phenotypic profiles within tissue samples. This new technology for the University will enable deep characterisation of tissues to identify which cells are present, where they are located in tissue, their biomarker co-expression patterns, and how they organize and interact to influence the tissue microenvironment. Lot 1: The University of Dundee School of Medicine require a spatial biology platform to embed this cutting-edge technology to map the spatial architecture of cells and phenotypic profiles within tissue samples. This new technology for the University will enable deep characterisation of tissues to identify which cells are present, where they are located in tissue, their biomarker co-expression patterns, and how they organize and interact to influence the tissue microenvironment. The multiplex platform will be embedded within the University’s Tayside Biorepository and be provided as a university wide translational science core facility service. The equipment will be used by over 20 research groups across the Schools of Medicine and Life Sciences in a broad reach of research programs, including translational research, molecular and cellular medicine, cancer research, neuroscience and infection and immunity. This will provide a significant opportunity to characterise disease progression and responses to therapy within translational research and clinical trials to support patient stratification and biomarker and drug development.