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Freeze Dryer Phase II

Published

Description

To replace the PLC hardware for CS15 and CS150 with up-to-date equivalents that align with the Schneider upgrade path.<br/>To replace the HMI hardware for CS15 and CS150 with up-to-date equivalents that align with those used in Phase 1.<br/>To recreate the functionality of CS15 and CS150 PLCs like-for-like following the Schneider upgrade path.<br/>To re-create the CS15 and CS150 HMIs and allow for development of further requirement defined in collaboration with the MHRA. Lot 1: To replace the PLC hardware for CS15 and CS150 with up-to-date equivalents that align with the Schneider upgrade path.<br/>To replace the HMI hardware for CS15 and CS150 with up-to-date equivalents that align with those used in Phase 1.<br/>To recreate the functionality of CS15 and CS150 PLCs like-for-like following the Schneider upgrade path.<br/>To re-create the CS15 and CS150 HMIs and allow for development of further requirement defined in collaboration with the MHRA.<br/>1.       Project Definition<br/>–     All parties to agree scope and ensure that everything is available for project commencement. <br/>–     MHRA to provide any existing software backups (PLC / SCADA source code).<br/>–     For software that is not available (such as the HMI), the supplier is expected to work with the MHRA to develop the requirements for the HMI.<br/>–     Both parties to agree deliverable format (e.g. schematic updates).<br/>2.       Part Selection<br/>–     Using the information gathered at the project definition stage, the supplier will select updated hardware and software packages for the PLCs, HMIs, SCADAs, data historian and anti-virus software.<br/>3.       Electrical Design<br/>–     With appropriate parts selected, the supplier will need to assess how the electrical design will be impacted by the proposed changes.<br/>–     These impacts should be minimised wherever possible.<br/>–     However, if changes are required, the supplier will need to modify any schematics while aligning with appropriate standards.<br/>4.       Software Development<br/>–     Software development for the PLC, HMI, SCADA and Data Historian can be started following on from part selection.<br/>–     This will require the supplier to migrate functionality where possible.<br/>–     Where the code cannot be migrated, the functionality will need to be replicated.<br/>–     The HMI should be re-built to meet the requirements based on existing SCADA screens and workshops held with MHRA operators.<br/>5.       FAT (Factory Acceptance Testing)<br/>–     The control cabinets and associated hardware shall not be moved from the MHRA facility.<br/>–     FAT is expected to test as much of the new software and hardware as possible without replicating site hardware.<br/>6.       Plant Upgrades<br/>–     This will include the MHRA ensuring that appropriate ethernet connection shall be made available and new virtual machines are available.<br/>7.       SAT (Site Acceptance Testing)<br/>–     SAT will need to be staggered to reduce any concurrent downtime to the freeze dryers. This will require testing and commissioning only one freeze dryer at a time.<br/>–     SAT is expected to test all software and hardware associated with the replacement hardware and the existing site hardware.<br/>8.       On-going contract Support<br/>–     Support is expected for the warranty of the system following from SAT and moving onto general support for the years following the warranty end.<br/>–     During these periods, the supplier is expected to ensure that recommend patches will not cause un-planned downtime.<br/>–     It is desired that the supplier can also provide support for the Phase 1 system (CS100).

Timeline

Publish date

9 months ago

Buyer information

Medicines and Healthcare products Regulatory Agency

Contact:
Jonathon Liam Moloney
Email:
jonathon.moloney@mhra.gov.uk

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