An Automated Platform for Optimisation of Downstream Processes

Description

NIBRT wish to procure an automated solution for the optimisation of downstream process development. The ideal solution would comprise of robotic liquid handling and scaled down chromatography capability to enable optimisation of purification parameters using design of experiments and subsequent seamless scale up to lab or pilot scale chromatographic purification. The automated platform will be used for optimisation of downstream processing of recombinant proteins, monoclonal antibodies, viral vectors and other biopharmaceutical formats. Ideally, the robotic capability of the platform should also be capable of automated sample preparation for analysis of the samples generated from on deck downstream process optimisation.