Biological Sample Processing, Genotyping, and Storage

Description

The scope of the procurement is receipt, processing and DNA extraction of blood samples from 5 million participants; design, manufacture and assessment of a high-throughput genome-wide genotype assay; the provision of a genotype service; and ultra-low temperature, long term storage of plasma, buffy coat, and DNA. The aim for commencement of these agreements is December 2021. Lot 1 - England: Biological sample Receipt & Processing The aim of Our Future Health is to recruit up to five million adults from across the UK to take part in the largest research study of its kind. Participants will be asked to provide information about their health and lifestyles and small sample of their blood. We will ask for permission to combine the information and samples that they give us with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases. We will use the health information, including genetic data, to calculate disease risk scores for participants in Our Future Health where possible. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of new 'genetic risk scores' in health care. In order to achieve this aim, Our Future Health needs to contract for services to process 2 x 6 ml EDTA blood samples from each of the 5 million participants with the aim to commence from December 2021. Processing will include barcode scanning receipt, fraction separation by centrifugation, aliquoting of plasma and buffy coat, DNA extraction, quantification and normalisation, temporary storage at low and ultra-low temperatures, effective IT and LIMS for tracking all child aliquots, and shipment of specimens for long term storage or genotyping. Additional information: To respond to this opportunity please click here: https://www.delta-esourcing.com/respond/67M68523U5 Access code for Lot 1 is; 67M68523U5 Lot 2 - Scotland: Biological sample Receipt & Processing The aim of Our Future Health is to recruit up to five million adults from across the UK to take part in the largest research study of its kind. Participants will be asked to provide information about their health and lifestyles and a small sample of their blood. We will ask for permission to combine the information and samples that they give us with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases. We will use the health information, including genetic data, to calculate disease risk scores for participants in Our Future Health where possible. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of new 'genetic risk scores' in health care. In order to achieve this aim, Our Future Health needs to contract for services to process 2 x 6 ml EDTA blood samples from each of the 5 million participants with the aim to commence from December 2021. barcode scanning receipt, fraction separation by centrifugation, aliquoting of plasma and buffy coat, DNA extraction, quantification and normalisation, samples at with temporary storage at low and ultra-low temperatures, effective IT and LIMS for tracking all child aliquots, and shipment of specimens for long term storage or genotyping. Additional information: To respond to this opportunity please click here: https://www.delta-esourcing.com/respond/639AY67J52 Access code for Lot 2 is 639AY67J52 Lot 3 - Wales: Biological sample Receipt & Processing The aim of Our Future Health is to recruit up to five million adults from across the UK to take part in the largest research study of its kind. Participants will be asked to provide information about their health and lifestyles and small sample of their blood. We will ask for permission to combine the information and samples that they give us with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases. We will use the health information, including genetic data, to calculate disease risk scores for participants in Our Future Health where possible. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of new 'genetic risk scores' in health care. In order to achieve this aim, Our Future Health needs to contract for services to process 2 x 6 ml EDTA blood samples from each of the 5 million participants with the aim to commence from December 2021. Processing will include barcode scanning receipt, fraction separation by centrifugation, aliquoting of plasma and buffy coat, DNA extraction, quantification and normalisation, temporary storage at low and ultra-low temperatures, effective IT and LIMS for tracking all child aliquots, and shipment of specimens for long term storage or genotyping. Additional information: To respond to this opportunity please click here: https://www.deltaesourcing.com/respond/639AY67J52 Access code for Lot 3 is 639AY67J52 Lot 4 - Northern Ireland: Biological sample Receipt & Processing The aim of Our Future Health is to recruit up to five million adults from across the UK to take part in the largest research study of its kind. Participants will be asked to provide information about their health and lifestyles and small sample of their blood. We will ask for permission to combine the information and samples that they give us with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases. We will use the health information, including genetic data, to calculate disease risk scores for participants in Our Future Health where possible. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of new 'genetic risk scores' in health care. In order to achieve this aim, Our Future Health needs to contract for services to process 2 x 6 ml EDTA blood samples from each of the 5 million participants with the aim to commence from December 2021. Processing will include barcode scanning receipt, fraction separation by centrifugation, aliquoting of plasma and buffy coat, DNA extraction, quantification and normalisation, temporary storage at low and ultra-low temperatures, effective IT and LIMS for tracking all child aliquots, and shipment of specimens for long term storage or genotyping. Additional information: To respond to this opportunity please click here: https://www.delta-esourcing.com/respond/639AY67J52 Access code for Lot 4 is 639AY67J52 Lot 5: Genotype assay - design/manufacture NOTE: The design and manufacture can happen outside of the Place of Performance but all genotyping and data processing of Customer-supplied quality control must be conducted within the boundaries of the Place of Performance. The aim of Our Future Health is to recruit up to five million adults from across the UK to take part in the largest research study of its kind. Participants will be asked to provide information about their health and lifestyles and small sample of their blood. We will ask for permission to combine the information and samples that they give us with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases. We will use the health information, including genetic data, to calculate disease risk scores for participants in Our Future Health where possible. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of new 'genetic risk scores' in health care. In order to achieve this aim, Our Future Health needs to contract for services to design, manufacture and quality control assess a genotype assay that could be applied to process 5 million participants with the aim to commence an agreement from December 2021. Additional information: To respond to this opportunity please click here: https://www.delta-esourcing.com/respond/3XGB99977T Access code for Lot 5 is 3XGB99977T Lot 6: Genotyping service provision The aim of Our Future Health is to recruit up to five million adults from across the UK to take part in the largest research study of its kind. Participants will be asked to provide information about their health and lifestyles and small sample of their blood. We will ask for permission to combine the information and samples that they give us with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases. We will use the health information, including genetic data, to calculate disease risk scores for participants in Our Future Health where possible. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of new 'genetic risk scores' in health care. In order to achieve this aim, Our Future Health needs to contract for services to genotype 5 million DNA samples using the genotype assay designed and manufactured by the awarded supplier of Lot 5, conduct genotype calling, and provide all results back to the Our Future Health. Additional information: To respond to this opportunity please click here: https://www.delta-esourcing.com/respond/67M68523U5 Access code for Lot 6 is 67M68523U5 Lot 7: Sample Storage and Access Management he aim of Our Future Health is to recruit up to five million adults from across the UK to take part in the largest research study of its kind. Participants will be asked to provide information about their health and lifestyles and small sample of their blood. We will ask for permission to combine the information and samples that they give us with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases. We will use the health information, including genetic data, to calculate disease risk scores for participants in Our Future Health where possible. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of new 'genetic risk scores' in health care. In order to achieve this aim, Our Future Health needs to contract for services for automated, ultra-low temperature, long term storage of up to 45 million cryovials of plasma, buffy coat, and DNA as well as access management of these samples. Additional information: To respond to this opportunity please click here: https://www.delta-esourcing.com/respond/4V872ZFEMH Access code for Lot 7 is 4V872ZFEMH